| Year | Festival | Category | Winner | Result |
|---|---|---|---|---|
| 2006 | Oscars | Best Actor | Philip Seymour Hoffman | Winner |
| 2006 | BAFTA | Best Leading Actor | Philip Seymour Hoffman | Winner |
| 2006 | Golden Globes | Best Actor - Drama | Philip Seymour Hoffman | Winner |
| 2006 | SAG Awards | Outstanding Performance by a Cast in a Motion Picture | Catherine Keener | Nominated |
| 2006 | Oscars | Best Director | Bennett Miller | Nominated |
| 2006 | BAFTA | Best Supporting Actress | Catherine Keener | Nominated |
| 2006 | Oscars | Best Supporting Actress | Catherine Keener | Nominated |